Every treatment that has ever made a difference in cancer care was once a part of a clinical trial. MUSC Hollings Cancer Center is committed to offering the best treatments available today while searching for even better ones for the future. Ask your doctor if a clinical trial is right for you.
STUDY13473 Randomized Controlled Trial of Olanzapine for the Control of Chemotherapy induced Vomiting in Children Receiving Highly Emetogenic Chemotherapy Chemotherapy-induced nausea and vomiting (CINV) are among the most bothersome symptoms during cancer treatment according to children and their parents. Most children receiving hematopoietic stem cell transplant (HSCT) conditioning experience CINV despite receiving antiemetic prophylaxis. Olanzapine improves CINV control in adult cancer patients, has a track record of safe use in children with psychiatric illness, does not interact with chemotherapy and is inexpensive. We hypothesize that the addition of olanzapine to standard antiemetics will improve chemotherapy-induced vomiting (CIV) control in children receiving high dose cyclophosphamide for hematopoietic stem cell transplantation (HSCT) conditioning. Study Information
STUDY17550 Internet Delivered Management of Pain Among Cancer Treatment Survivors (IMPACTS) To determine whether an Internet-based pain coping skills program plus enhanced usual care, compared to enhanced usual care alone, yields significant improvements in the co-primary outcomes of pain severity (as measured by the Brief Pain Inventory (BPI)) and pain interference (also measured by the BPI) from baseline to the post-intervention assessment for cancer survivors with persistent pain. Study Information
STUDY12888 The Impact of a Gravity versus Vacuum Based Indwelling Tunneled Pleural Drainage System on Pain: A Multicenter, Randomized Trial The objective of this investigation is to compare different drainage strategies of Indwelling Pleural Catheters (IPC) regarding patient quality of life and outcomes Study Information
STUDY19497 A Randomized Controlled Trial to Evaluate the Survivorship Needs Assessment Planning Tool for Head and Neck Cancer Survivor Caregiver Dyads To evaluate the effects of SNAP on: a) caregiver burden in caregivers, b) symptom severity in survivors and c) psychological well-being in head and neck cancer survivors and caregivers 6 months after completing SNAP Study Information
STUDY20136 The Effect of a Collaborative Art Therapy and Physical Therapy Intervention on Children Undergoing a Hematopoietic Cell Transplant (HCT): a Randomized Clinical Trial In children undergoing HCT during in-patient care, does a randomized group receiving a combination of PT plus AT have improved functional activity level outcomes of selfcare and mobility as measured by the Pediatric Evaluation of Disability Inventory Computerized Adaptive Test (PEDI CAT) and the 6-Minute Walk Test (6MWT), compared with a group receiving PT only.Do children receiving PT plus AT have different physiological (sympathetic or parasympathetic) and emotional responses to oil pastels and gouache as measured by respiratory sinus arrhythmia (RSA) derived from heart rate variability (HRV) and Self-Assessment Manikin (SAM) scores during each of the daily AT sessions. In children receiving PT plus AT, determine if there is a stronger association between the RSA values of oil pastels or gouache AT and an increased walking distance as measured by accelerometry during daily PT sessions. Study Information