Clinical Trials

Every treatment that has ever made a difference in cancer care was once a part of a clinical trial. MUSC Hollings Cancer Center is committed to offering the best treatments available today while searching for even better ones for the future. Ask your doctor if a clinical trial is right for you.

 

Supportive Care Trials

 

  • STUDY13473

    Randomized Controlled Trial of Olanzapine for the Control of Chemotherapy induced Vomiting in Children Receiving Highly Emetogenic Chemotherapy

    Chemotherapy-induced nausea and vomiting (CINV) are among the most bothersome symptoms during cancer treatment according to children and their parents. Most children receiving hematopoietic stem cell transplant (HSCT) conditioning experience CINV despite receiving antiemetic prophylaxis. Olanzapine improves CINV control in adult cancer patients, has a track record of safe use in children with psychiatric illness, does not interact with chemotherapy and is inexpensive. We hypothesize that the addition of olanzapine to standard antiemetics will improve chemotherapy-induced vomiting (CIV) control in children receiving high dose cyclophosphamide for hematopoietic stem cell transplantation (HSCT) conditioning.

    Study Information



  • STUDY17550

    Internet Delivered Management of Pain Among Cancer Treatment Survivors (IMPACTS)

    To determine whether an Internet-based pain coping skills program plus enhanced usual care, compared to enhanced usual care alone, yields significant improvements in the co-primary outcomes of pain severity (as measured by the Brief Pain Inventory (BPI)) and pain interference (also measured by the BPI) from baseline to the post-intervention assessment for cancer survivors with persistent pain.

    Study Information



  • STUDY12888

    The Impact of a Gravity versus Vacuum Based Indwelling Tunneled Pleural Drainage System on Pain: A Multicenter, Randomized Trial

    The objective of this investigation is to compare different drainage strategies of Indwelling Pleural Catheters (IPC) regarding patient quality of life and outcomes

    Study Information



  • STUDY19497

    A Randomized Controlled Trial to Evaluate the Survivorship Needs Assessment Planning Tool for Head and Neck Cancer Survivor Caregiver Dyads

    To evaluate the effects of SNAP on: a) caregiver burden in caregivers, b) symptom severity in survivors and c) psychological well-being in head and neck cancer survivors and caregivers 6 months after completing SNAP

    Study Information



  • STUDY18274

    A Multi Site Randomized Clinical Trial Comparing a Brief Tele Cognitive Behavioral Therapy Intervention (BRIGHT) with Attention Control for the Management of Body Image Related Distress Among Head and Neck Cancer Survivors

    To evaluate the efficacy of BRIGHT compared with attention control (AC) on HNC-related BID as measured by change from baseline in the IMAGE­HN score.

    Study Information