Clinical Trials

Sponsor: PMV Pharmaceuticals, Inc.

Sponsor Study ID: PMV-586-101

Study Title: A Phase 1/2 Open label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation (PYNNACLE)

CTO #: 103704

NCT Number: NCT04585750

Phase: I/II

Protocol Type: Treatment

Age Group: Adults

Disease Sites: Breast, Colon, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Ovary, Pancreas, Prostate, Soft Tissue, Stomach, Thyroid

Study Objectives: This study will assess the safety and tolerability of multiple dose levels of PC14586 in participants with advanced solid tumors containing a p53 Y220C mutation.



Study Documents    
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